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Poster: Arbuthnot Date: May 17, 2013 11:26am
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

purely fringe stuff is right, as i was surprised i had not heard anything on this prior to today ... as for the author of the article i linked to, i had actually heard him several years back on the radio program coast-to-coast, on some UFO stuff (freaky things can be heard on the radio after midnight), but either way, still pretty interesting ... i am curious about the full DNA analysis that apparently is forthcoming in about a year's time (yes, i know you stated a few days time for DNA analysis, but perhaps ancient DNA requires some other process/approach that requires a different timeframe??

regardless, thanks for giving your thoughts

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Poster: William Tell Date: May 17, 2013 11:43am
Forum: GratefulDead Subject: Re: Fascinating! ... original model for 68 artwork discovered!!!

If it were in a lab w well funded sorts, like elb, where we are curing cancer and doing other great things, they can fast track stuff and do it quick...you are right that "old" or "dead" (ie, preserved) DNA is troublesome, but this wouldn't be too bad, given the timeline.

Of course, this is ALL highly speculative on my part--I really just scanned it, but like you and elb, have some reservations about the presentation, etc.

Cool find though--he's a NATURAL for being a 68 lover, right?

I mean, really! He could've been a MODEL for the Aoxomoxoa cover, right?

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Poster: ColdRain108 Date: May 17, 2013 12:10pm
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

they need to send it to the set of one of the vast myriad of CSI TV shows, they'll have that DNA analyzed in less than 15 minutes!

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Poster: Mandojammer Date: May 17, 2013 1:37pm
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

I'd put a whole lot more behind the story if they had performed a Polymerase Chain Reaction (PCR) DNA analysis instead of talking about it in glittering generalities.

Anyone know how long a full PCR analysis takes?

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Poster: beep* Date: May 18, 2013 7:47am
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

Long enough to discover.....what I feared more than anything.

Image4.jpg

This post was modified by beep* on 2013-05-18 14:47:18

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Poster: jgIynn1.2 Date: May 21, 2013 1:21pm
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

Exactly what popped into my head when I saw the x-ray. Same posture and everything.

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Poster: elbow1126 Date: May 17, 2013 4:07pm
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

What they are doing is way better than PCR. They are doing a form of next generation sequencing to identify mutations in any gene in the genome. I can't figure out from the article (AAAS link not the one Arb originally linked which was silly in its description) if they are just sequencing the coding part of the genome (typically called exome sequencing) or are sequencing the entire genome (whole genome sequencing or WGS). my guess is its the former as it represents about 1% of the total DNA. It takes about 4-6 weeks to sequence a genome now, but thats the easy part. The bioinformatics to map the sequences against a reference sequence and to scan for mutations is where it gets a little trickier. I think WGS takes up about 1 TB/genome.

The reason i suspect they are doing exome sequencing is to look for single base (point) mutations in genes, but to be sure they don't pick up a false positive the sequencing is done in a massively paralleled fashion so that you cover each gene many times. Remember you have two copies of each gene and the mutation might only be in one. Sounds like they have mapped and analyzed about 15% of the genome so far and specifically went after genes that would show the thing was human (mitochondrial genes) and that are known to be mutated in dwarfism, where they have come up empty. Now they have to look carefully at the rest of the genome. Will it take a year? Not sure but, if they find a mutation they will need to confirm with a conventional sequencing approach. So it might be a year before we hear the results.

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Poster: William Tell Date: May 17, 2013 4:46pm
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

Ah, well, you clearly have a better understanding than I; I only read the first link, and it was NOT encouraging, on any number of fronts, so I bailed...it seems like the folks, or one at least, want to wrap it in an air of "extra special, mysterious" research...rather than straight up "what kind of genetic oddball is it?", which frankly, I wouldn't think is the logical first pass at explaining the existance of a strange looking little person, eh? IE, why not "environment" first?

But, again, it was the lack of upfront, "here we have a HUMAN of singular development, and we are looking for..." and more of "ET?"...was it just me skimming it?

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Poster: elbow1126 Date: May 17, 2013 7:40pm
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

No the guy who wrote the first article was definitely sensationalizing it and holding out hope that they found that space alien from the Flintstones cartoons. You remember the little dude who hung out with Fred and Barney but no one else could see? I think his name was Kazoo or something like that. The only reason i thought it wasn't a farce was i recognized Garry Nolan's name and knew he is at Stanford. We use a cell line that his lab created that makes it easy to transfer genes into other cells.

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Poster: high flow Date: May 17, 2013 2:38pm
Forum: GratefulDead Subject: Re: Fascinating! ... If Not A Hoax [non-JG]

OJ Simpson?